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Quantitative analysis of trace-level bleomycin in complex matrices
Helena Plešnik, Angelika Vižintin, Damijan Miklavčič, Jack Steed, Jianru Stahl-Zeng, Tina Kosjek
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Oznake: bleomicin;elektrokemoterapija;natančnost meritev;bleomycin;electrochemotherapy;trace level;tandem mass spectrometry;sensitivity;
Bleomycin, a cytotoxic antibiotic, poses substantial challenges for mass spectrometry-based analysis due to its extreme polarity, chelating properties, heterogeneity of fractions, and propensity to form multiple charged species during electrospray ionization. As one of the few effective drugs used i ...
Leto: 2025 Vir: Fakulteta za elektrotehniko (UL FE)
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