Št. zadetkov: 22
Pregledni znanstveni članek
Oznake:
eksosom;mikrookolje;vnetje;exosome;microenvironment;inflammation;
Glioblastoma is simultaneously the most common and most aggressive primary brain tumor in the central nervous system, with poor patient survival and scarce treatment options. Most primary glioblastomas reoccur and evolve radio- and chemoresistant properties which make them resistant to further treat ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
CAR-T;glioblastom;imunoterapija;
Glioblastoma is the most common and lethal brain malignancy. Standard treatment consists of surgery, radiotherapy and chemotherapy, and results in life expectancy of 15 months after diagnosis. Due to the specific location of the tumor, designing new drugs is complicated and expensive. Drug repur- po ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
3D biotisk;3D modeli celičnih kultur;invazija;migracija;rak jajčnikov;sferoidi;
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
dolgo nekodirana RNA;shizofrenija;depresija;long noncoding RNA;schizophrenia;depression;
Understanding the pathology of psychiatric disorders is challenging due to their complexity and multifactorial origin. However, development of high-throughput technologies has allowed for better insight into their molec-ular signatures. Advancement of sequencing methodologies have made it possible t ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
nanomateriali;rak možganov;nanomedicina;nanomaterials;brain cancer;nanomedicine;
Advances in technology of the past decades led to development of new nanometer scale diagnosis and treatment approaches in cancer medicine leading to establishment of nanooncology. Inorganic and organic nanomaterials have been shown to improve bioimaging techniques and targeted drug delivery systems ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
glioblastom;možganski rak;nekodirani genom;biološki označevalec;prognoza;glioblastoma;brain cancer;noncoding genome;biomarker;prognosis;
Glioblastoma is the most aggressive and lethal primary brain malignancy, with an average patient survival from diagnosis of 14 months. Glioblastoma also usually progresses as a more invasive phenotype after initial treatment. A major step forward in our understanding of the nature of glioblastoma wa ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
glioblastoma;extracellular vesicles;nanoscience;
Owing to the advancement of technology combined with our deeper knowledge of human nature and diseases, we are able to move towards precision medicine, where patients are treated at the individual level in concordance with their genetic profiles. Lately, the integration of nanoparticles in biotechno ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
glioblastoma;heterogeneity;non-animal models;treatmet predicition;
Glioblastoma is an extremely lethal cancer characterized by great heterogeneity at different molecular and cellular levels. As a result, treatment options have moved far from systemic and universal therapies toward targeted treatments and personalized medicine. However, for successful translation fr ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
glioblastoma;B7-H3;CD276;signaling pathways;immune checkpoints;immunotherapy;
Cancer has emerged as the second most prevalent disease and the leading cause of death, claiming the lives of 10 million individuals each year. The predominant varieties of cancer encompass breast, lung, colon, rectal, and prostate cancers. Among the more aggressive malignancies is glioblastoma, cat ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
citoskelet;glioblastom;označevalci;cytoskeleton;glioblastoma;biomarkers;
Glioblastoma, the most common primary brain malignancy, is an exceptionally fatal cancer. Lack of suitable biomarkers and efficient treatment largely contribute to the therapy failure. Cytoskeletal proteins are crucial proteins in glioblastoma pathogenesis and can potentially serve as biomarkers and ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)