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Št. zadetkov: 3
Epigenetics of Alzheimer's disease
Matea Nikolac Perkovic, Alja Videtič, Marcela Konjevod, Katarina Kouter, Dubravka Svob Strac, Gordana Nedic Erjavec, Nela Pivac
Pregledni znanstveni članek
Oznake: Alzheimerjeva bolezen;epigenetika;metilacija DNA;Alzheimer's disease;epigenetics;DNA methylation;
There are currently no validated biomarkers which can be used to accurately diagnose Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies. Moreover, to date, only symptomatic treatments exist for this progressive neurodegenerative disorder. In the search for new ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Difference in methylation and expression of brain-derived neurotrophic factor in Alzheimer’s disease and mild cognitive impairment
Katarina Kouter, Matea Nikolac Perkovic, Gordana Nedic Erjavec, Tina Milos, Lucija Tudor, Suzana Uzun, Ninoslav Mimica, Nela Pivac, Alja Videtič, Alja Videtič
Izvirni znanstveni članek
Oznake: epigenetics;DNA methylation;Alzheimer’s dementia;
Due to the increasing number of progressive dementias in the population, numerous studies are being conducted that seek to determine risk factors, biomarkers and pathological mechanisms that could help to differentiate between normal symptoms of aging, mild cognitive impairment (MCI) and dementia. T ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Metabolomic Profiling of Extracellular Vesicles Reveals Distinct Metabolic Dysregulation and Treatment-Specific Signatures in Depression
Nikola Balic, Gordana Nedic Erjavec, Marcela Konjevod, Jorge Saiz, Tina Curkovic, Lucija Tudor, Dubravka Svob Strac, Alja Videtič, Julija Šmon, Magda Tušek-Žnidarič
Izvirni znanstveni članek
Oznake: MDD;TRD;metabolomics;extracellular vesicles;duloxetine;bright-light therapy;esketamine;treatment;
Major depressive disorder (MDD) is associated with complex metabolic alterations. In this study, we applied a multiplatform metabolomics approach (GC-MS and LC-MS) to characterize the plasma extracellular vesicle (EV) metabolome in healthy controls (N = 50), responsive MDD patients (N = 60), and pat ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 3
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