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Št. zadetkov: 3
Mitochondrial sensitivity to submaximal [ADP] following bed rest
Lucrezia Zuccarelli, Maria De Martino, Antonio Filippi, Alice E. Knapton, Benjamin D. Thackray, Giovanni Baldassarre, Boštjan Šimunič, Rado Pišot, Giuseppe Sirago, Elena Monti, Marco Narici, Miriam Isola, Andrew J. Murray, Giovanna Lippe, Bruno Grassi
Izvirni znanstveni članek
Oznake: ADP;ležanje v postelji;občutljivost mitohondrijev;težke verige miozina;mitohondriji skeletnih mišic;bed rest;mitochondrial sensitivity;myosin heavy chains;skeletal muscle mitochondria;
Background: We recently demonstrated that following a 10-day exposure to inactivity/simulated microgravity impairments ofoxidative metabolism were located ‘upstream’ of mitochondrial function, as evaluated by maximal ADP-stimulated mitochon-drial respiration (JO 2max) determined ex vivo. The aim of ...
Leto: 2025 Vir: Repozitorij Univerze na Primorskem (RUP)
Preserved mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10-day bed rest in older adults
Evgeniia Motanova, Lucrezia Zuccarelli, Evgenii Lysenko, Stefano Amoretti, Marco Pirazzini, Ornella Rossetto, Lorenza Brocca, Roberto Bottinelli, Maria Antonietta Pellegrino, Giovanni Baldassarre, Clarissa Gissi, Giovanna Lippe, Mladen Gasparini, Boštjan Šimunič, Rado Pišot, Bruno Grassi, Marco Narici
Izvirni znanstveni članek
Oznake: skeletal muscle;mitochondria;older adults;physical inactivity;mitochondrial respiration;
Ageing affects mitochondrial integrity in skeletal muscle, and physical inactivity may further exacerbate these changes. Although mitochondrial alterations are documented in ageing and disuse independently, how disuse impacts the mitochondrial phenotype in older populations remains unclear. This wor ...
Leto: 2026 Vir: Repozitorij Univerze na Primorskem (RUP)
Impact of sedentarism due to the COVID-19 home confinement on neuromuscular, cardiovascular and metabolic health
Marco Narici, Giuseppe De Vito, Martino V. Franchi, Antonio Paoli, Tatiana Moro, Giuseppe Marcolin, Bruno Grassi, Giovanni Baldassarre, Lucrezia Zuccarelli, Gianni Biolo, Filippo Giorgio Di Girolamo, Nicola Fiotti, F. Dela, Paul L. Greenhaff, Constantinos Maganaris
Izvirni znanstveni članek
Oznake: COVID-19;sedentarism;neuromuscular system;cardiovascular system;glucose homeostasis;body composition;nutrition;exercise;
The COVID-19 pandemic is an unprecedented health crisis as entire populations have been asked to self-isolate and live in home-confinement for several weeks to months, which in itself represents a physiological challenge with significant health risks. This paper describes the impact of sedentarism o ...
Leto: 2021 Vir: Repozitorij Univerze na Primorskem (RUP)
Št. zadetkov: 3
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