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Št. zadetkov: 2
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Adham S. Bear, Tatiana Blanchardt, Joseph Cesare, Michael J. Ford, Lee P. Richman, Chong Xu, Miren L. Baroja, Sarah McCuaig, Christina Costeas, Khatuna Gabunia, John Scholler, Avery D. Posey, Mark H. OʹHara, Anže Smole, Daniel J. Powell, Benjamin A. Garcia, Robert H. Vonderheide, Gerald P. Linette, Beatriz M Carreno
Izvirni znanstveni članek
Oznake:
Activating RAS missense mutations are among the most prevalent genomic alterations observed in human cancers and drive oncogenesis in the three most lethal tumor types. Emerging evidence suggests mutant KRAS (mKRAS) may be targeted immunologically, but mKRAS epitopes remain poorly defined. Here we e ...
Leto: 2021 Vir: Nacionalni inštitut za biologijo (NIB)
Splenic irradiation for myelofibrosis prior to hematopoietic cell transplantation
Nico Gagelmann, Gabriela S. Hobbs, Edoardo Campodonico, Grzegorz Helbig, Polona Novak, Thomas Schroeder, Artur Schneider, Christina Rautenberg, Hans Christian Reinhardt, Linette Bosques
Izvirni znanstveni članek
Oznake: aplastic anemia;children;
Splenomegaly is the clinical hallmark of myelofibrosis. Splenomegaly at the time ofallogeneic hematopoietic cell transplantation (HCT) is associated with graft failureand poor graft function. Strategies to reduce spleen size before HCT especially after ailure to Janus kinase (JAK) inhibition represe ...
Leto: 2024 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 2
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