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Št. zadetkov: 2
Effective targeting of E2F1 transcription factor via siRNA gene electrotransfer in HT-29 colorectal carcinoma xenografts
Tanja Dolinšek, Simona Kranjc, Živa Modic, Tim Božič, Boštjan Markelc, Monica Cazzato, Gabriele Grassi, Maja Čemažar
Izvirni znanstveni članek
Oznake: kolorektalni rak;E2F1;GET;elektroprenos genov;colorectal carcinoma;gene electrotransfer;
Colorectal cancer (CRC) remains a significant global health concern, with survival outcomes heavily dependent on the stage at diagnosis. Targeted therapies offer a promising approach to improve patient outcomes, particularly by addressing molecular drivers of tumor progression. One such target is th ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Polymer-mediated delivery of siRNAs to hepatocellular carcinoma
Rossella Farra, Francesco Musiani, Francesca Perrone, Maja Čemažar, Urška Kamenšek, Federica Tonon, Michela Abrami, Aleš Ručigaj, Mario Grassi, Gabriele Pozzato, Deborah Bonazza
Pregledni znanstveni članek
Oznake: izboljšana dostava učinkovin;onkološka zdravila;rak jeter;hepatocelularni rak;optimized drug delivery;anticancer drugs;HCC;siRNA;
Despite the advances in anticancer therapies, their effectiveness for many human tumors is still far from being optimal. Significant improvements in treatment efficacy can come from the enhancement of drug specificity. This goal may be achieved by combining the use of therapeutic molecules with tumo ...
Leto: 2018 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 2
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