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Št. zadetkov: 3
ǂThe ǂimpact of histopathology on prognosis of squamous cell carcinoma of the larynx
Nina Zidar, Nina Zidar, Lester D. R. Thompson, Abbas Agaimy, Göran Stenman, Henrik Hellquist, Alfons Nadal, Antti A. Mäkitie, Fernando López, Primož Strojan, Alfio Ferlito
Pregledni znanstveni članek
Oznake: larynx;biomarkers;disease progression;human papillomavirus;lymphocytes;tumour-infiltrating;morbidity;precision medicine;prognosis;squamous cell carcinoma;
Despite decades of progress, laryngeal squamous cell carcinoma (SCC) is still associated with significant morbidity and mortality worldwide. Additional biomarkers are needed to apply precision medicine and predict the clinical course. We reviewed and summarised routinely reported histopathologic fea ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Biomarkers for predicting malignant transformation of premalignant lesions of the larynx
Juan P. Rodrigo, Juan P. Rodrigo, Reydson Alcides de Lima-Souza, Fernando López, Göran Stenman, Abbas Agaymy, Miquel Quer, Vinidh Paleri, Ilmo Leivo, Alfons Nadal, Nina Zidar, Nina Gale
Izvirni znanstveni članek
Oznake: ROBINS-I;biomarkers;laryngeal dysplasia;malignant transformation;premalignant lesions;systematic review;
Background/Objectives: Premalignant laryngeal lesions carry a variable risk of malignant transformation to squamous cell carcinoma. Identifying reliable biomarkers that predict malignant transformation could improve patient management and surveillance strategies. The objective of this work is to per ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Epigenetic alterations in head and neck cancer
Henrik Hellquist, Henrik Hellquist, Pedro Castelo-Branco, Göran Stenman, Alfons Nadal, Abbas Agaimy, Nina Zidar, Reydson Alcides de Lima-Souza, Fernanda Viviane Mariano, Andrés Coca-Pelaz, Alfio Ferlito
Pregledni znanstveni članek
Oznake: clinical implications;epigenetics;head and neck cancer;methylation;tumour suppressor genes;
DNA methylation of tumour suppressor genes is the most well-studied epigenetic alterations in head and neck cancer. The tumour suppressor genes CDKN2A, RASSF1, and TIMP3 are the most frequently investigated, but the methylation status has been analysed in more than another dozen genes, for example M ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 3
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