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Št. zadetkov: 3
High-field diffusion tensor imaging of median, tibial, and sural nerves in type 2 diabetes with morphometric analysis
Luka Pušnik, Luka Pušnik, Aljoša Gabor, Barbara Radochová, Jiří Janáček, František Saudek, Armin Alibegović, Igor Serša, Erika Cvetko, Nejc Umek, Žiga Snoj
Izvirni znanstveni članek
Oznake: difussion tensor;fractional anisotropy;histology;magnetic resonance imaging;microscopy;optical projection tomography;
Background and purpose: The primary objective was to compare diffusion tensor imaging (DTI) scalar parameters of peripheral nerves between subjects with type 2 diabetes mellitus (T2DM) and those without diabetes. Secondarily, we aimed to correlate DTI scalar parameters with nerve morphometric proper ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Characterization of diabetes-related biomechanical and structural alterations in human deep fasciae using atomic force microscopy and multimodal multiphoton imaging
Chiedozie Kenneth Ugwoke, Chiedozie Kenneth Ugwoke, Borut Furlani, Daniel Hadraba, Jiří Janáček, Erika Cvetko, Jernej Jorgačevski, Marko Kreft, Robert Zorec, František Saudek, Nejc Umek
Izvirni znanstveni članek
Oznake: advanced glycation end-products;atomic force microscopy;deep fascia;extracellular matrix remodeling;multiphoton imaging;type 2 diabetes mellitus;
Background: Type 2 diabetes mellitus (T2DM) is associated with connective-tissue complications, but effects on human deep fascia remain poorly understood. This study employed atomic force microscopy (AFM) nanoindentation and multiphoton imaging to quantify region-specific biomechanical and structura ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Fibre morphology, intramyocellular lipid content and 3D capillary architecture in human postural, respiratory and locomotor muscles in type 2 diabetes mellitus
Nataša Pollak, Nataša Pollak, Jiří Janáček, František Saudek, Erika Cvetko, Barbara Radochová, Armin Alibegović, Chiedozie Kenneth Ugwoke, Alessandro Davide Basello, Žiga Šink, Luka Pušnik, Rok Tit Tomazin, Nejc Umek
Izvirni znanstveni članek
Oznake: 3D capillary morphometry;intramyocellular lipid;metabolic myopathy;myosin heavy chain isoforms;skeletal muscle;type 2 diabetes mellitus;
In type 2 diabetes mellitus (T2DM), skeletal muscle is a major site of metabolic and microvascular dysfunction, yet most human data derive from large locomotor muscles, whereas postural and respiratory muscles remain less well characterised. We examined whether T2DM alters fibre morphology, intramyo ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 3
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