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Novel nastorazepide-based radioligands demonstrate excellent cholecystokinin-2 receptor targeting and theranostic potential
Lennart Bohrmann, Doroteja Novak, Marko Krošelj, Raghuvir H. Gaonkar, Francesca Porto, Fani Melpomeni, Petra Kolenc-Peitl, Marko Anderluh, Marko Anderluh, Rosalba Mansi, Rosalba Mansi
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Oznake: cholecystokinin-2 receptor antagonists;CCK2R antagonists;nastorazepide;radioligands;SPECT/CT;peptide receptor radionuclide therapy;
Radiolabeled gastrin antagonists are emerging as a new tool for the diagnosis and treatment of cholecystokinin-2 receptor (CCK2R) expressing tumors such as medullary thyroid carcinoma and small cell lung cancer, overcoming limitations of agonist-based ligands. In this study, the CCK2R antagonist nas ...
Leto: 2026 Vir: Repozitorij Univerze v Ljubljani (RUL)
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