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Št. zadetkov: 2
Variants in TPH2 and ADARB1 genes in completed suicide from the Slovenian population
Jelena Karanović, Jelena Karanović, Špela Supej, Iris Šalamon, Maja Pantović-Stefanović, Maja Ivković, Tomaž Zupanc, Dušanka Savić Pavićević, Alja Videtič, Alja Videtič
Izvirni znanstveni članek
Oznake: ADARB1;suicidal behaviour;TPH2;rs4290270;rs4819035;
Introduction: Suicidal behaviour, including completed suicide and attempted suicide, is affected by genetic factors, involving serotonergic system genes. TPH2 gene encodes tryptophan hydroxylase 2, rate-limiting brain serotonin synthetising enzyme whose pre-mRNAs are edited by ADAR enzymes, includin ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Genetic predisposition of suicidal behavior
Jelena Karanović, Doroteja Beraković, Mojca Katrašnik, Iris Šalamon, Maja Pantović-Stefanović, Lana Radenković, Nemanja Garai, Maja Ivković, Dušanka Savić Pavićević, Tomaž Zupanc, Alja Videtič
Izvirni znanstveni članek
Oznake: association;genetic variant;single nucleotide polymorphism;suicidal behavior;
Completed suicide accounts for over 700,000 deaths worldwide annually, while attempted suicide is 20 times more frequent. Genetic background is an important factor contributing to suicidal behavior, including candidate genes in glutamate, γ-aminobutyric acid (GABA), and polyamine systems. Our aim wa ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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