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Plectin plays a role in the migration and volume regulation of astrocytes
Maja Žugec, Borut Furlani, Maria J. Castañón, Boštjan Rituper, Irmgard Fischer, Giuseppe Broggi, Rosario Caltabiano, Giuseppe M. V. Barbagallo, Michelino Di Rosa, Daniele Tibullo, Saša Simčič, Gorazd Bernard Stokin, Jernej Jorgačevski, Robert Zorec, Maja Potokar, Maja Potokar
Izvirni znanstveni članek
Oznake: aquaporin 4;astrocyte;cell migration;cell volume;cytoskeleton;edema;glioblastoma;intermediate filaments;plectin;
Background: The expression of aquaporin 4 (AQP4) and intermediate filament (IF) proteins is altered in malignant glioblastoma (GBM), yet the expression of the major IF-based cytolinker, plectin (PLEC), and its contribution to GBM migration and invasiveness, are unknown. Here, we assessed the contrib ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
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