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Characterization of diabetes-related biomechanical and structural alterations in human deep fasciae using atomic force microscopy and multimodal multiphoton imaging
Chiedozie Kenneth Ugwoke, Chiedozie Kenneth Ugwoke, Borut Furlani, Daniel Hadraba, Jiří Janáček, Erika Cvetko, Jernej Jorgačevski, Marko Kreft, Robert Zorec, František Saudek, Nejc Umek
Izvirni znanstveni članek
Oznake: advanced glycation end-products;atomic force microscopy;deep fascia;extracellular matrix remodeling;multiphoton imaging;type 2 diabetes mellitus;
Background: Type 2 diabetes mellitus (T2DM) is associated with connective-tissue complications, but effects on human deep fascia remain poorly understood. This study employed atomic force microscopy (AFM) nanoindentation and multiphoton imaging to quantify region-specific biomechanical and structura ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
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