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Novel short-acting non-depolarizing muscle relaxants derived from galantamine
Robert Frangež, Julien Rouleau, Jordi Molgó, Monika C. Žužek, Evelyne Benoit, Catherine Guillou
Izvirni znanstveni članek
Oznake: derivati ​​galantamina;mišični relaksanti;nikotinski acetilholinski receptorji;nevromuskularni prenos pri glodalcih;elektrofiziologija;kardiovaskularni sistem;serumski elektroliti;galantamine derivatives;muscle relaxants;nicotinic acetylcholine receptors;rodent neuromuscular transmission;electrophysiology;cardiovascular system;serum electrolytes;
This study evaluated two novel galantamine-derived compounds, DR-976 and compound 15, as potential short-acting, non-depolarizing muscle relaxants. The aim was to introduce a long carbon chain bearing a quaternary ammonium group on the galantamine scaffold, in order to redirect its pharmacological p ...
Leto: 2026 Vir: Veterinarska fakulteta (UL VF)
Št. zadetkov: 1
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