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Št. zadetkov: 3
Antikoagulacijsko zdravljenje pri bolnikih z zmanjšanim ledvičnim delovanjem
Gregor Tratar, Alenka Mavri, Mirjam Gubenšek, Barbara Krevel, Mateja Ježovnik, Nina Ostaševski, Monika Štalc, Tjaša Vižintin Cuderman
Pregledni znanstveni članek
Oznake:
Background In the recent years, the number of patients treated with anticoagulant therapy is increasing. Among them, there is also an increased number of patients with renal insufficiency. Due to changes in coagulation andfibrinolityc system activity these patients are at increased risk of bleeding ...
Leto: 2008 Vir: dLib.si Digitalna knjižnica Slovenije
Real-world effectiveness and cardiovascular outcomes of PCSK9 inhibitor therapy
Jan Kafol, Zlatko Fras, Marko Novaković, Laurence S. Sperling, Matija Cevc, Barbara Krevel, Lenart Kafol, Anamarija Kelenc, Klarisa Kepic, Katarina Vrbinc, Miha Švarc, Urh Grošelj, Borut Jug
Izvirni znanstveni članek
Oznake: zaviralci PCSK9;monoklonska protitelesa;siRNA;študije iz resničnega sveta;zdravilo inclisiran;zdravilo evolokumab;zdravilo alirokumab;LDL-C;intoleranca na statine;kardiovaskularni učinki;PCSK9 inhibitors;monoclonal antibodies;real-world study;inclisiran;evolocumab;alirocumab;statin intolerance;cardiovascular outcomes;
Background and Aims: Randomized trials showed efficacious lipid-lowering with PCSK9 inhibitors (PCSK9i), but real-world treatment is often limited by statin-associated side effects (SASE). We quantified the effectiveness, safety and cardiovascular outcomes of alirocumab, evolocumab and inclisiran in ...
Leto: 2026 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Universal screening for familial hypercholesterolemia in preschool children and their families in Slovenia (FH-FAMILIES)
Mia Becker, Bernarda Vogrin, Jan Kafol, Barbara Čugalj Kern, Urh Grošelj, Jernej Završnik, Matej Mlinarič, Ana Drole Torkar, Jaka Šikonja, Jernej Kovač, Tadej Battelino, Zlatko Fras, Matija Cevc, Borut Jug, Barbara Krevel, Tevž Gorjanc, Klara Zabkar, Aljaz Jamnik, Maruša Debeljak, Ana Grom, Tamara Grgic, Miha Švarc, Maja Filipič, Mineja Leban, Marija Kjoseva Bakarova, Mateja Šnajder, Alenka Koren, Mojca Mir Toplak, Mojca Ivankovič Kacjan, Mario Kulaš, Benjamina Trtnik, Saša Korez, Nina Hebar, Bernarda Vogel, Vesna Amon Prodnik, Lidija Pretnar, Janja Schweiger Nemanič
Izvirni znanstveni članek
Oznake: hypercholesterolemia;universal screening;preschoolers;total cholesterol;genetic testing;
Familial hypercholesterolemia (FH) is the most common metabolic disease, with prevalence estimated between 1:250 and 1:300. The affected individuals have a significantly higher risk for developing atherosclerosis and cardiovascular disease (CVD) compared to non-affected individuals. Early CVD can be ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 3
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