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Št. zadetkov: 2
Development of the fish invitrome for animal-free environmental risk assessment of chemicals
Marion Revel, Ksenia J Groh, Jessica Bertoli, Mihai-Ovidiu Degeratu, Melanie Fischer, Stephan Fischer, Jarno Hoekman, Barbara Jozef, Roman Li, Anže Županič
Izvirni znanstveni članek
Oznake: sistemska toksikologija;alternative eksperimentom na živalih;mavrična postrv;ekotoksikologija;new approach methodologies (NAMs);rainbow trout cell lines;toxicity testing;socio-technical approach;co-design with stakeholders;
Given the need to reduce animal testing for environmental risk assessment, we aim to develop a fish invitrome, an alternative fish modular framework capable of predicting chemical toxicity in fish without the use of animals. The central module of the framework is the validated RTgill-W1 cell line as ...
Leto: 2025 Vir: Nacionalni inštitut za biologijo (NIB)
ǂA ǂnew fibrillization mechanism of ß-lactoglobulin in glycine solutions
Matej Jaklin, Jozef Hritz, Barbara Hribar
Izvirni znanstveni članek
Oznake: ß-laktoglobulin;fibrilizacijski mehanizem;pufer specifični efekt;sferoidni oligomeri;ß-lactoglobulin;fibrillization mechanism;buffer specific effects;spheroid oligomers;
Even though amyloid aggregates were discovered many years ago the mechanism of their formation is still a mystery. Because of their connection to many of untreatable neurodegenerative diseases the motivation for finding a common aggregation path is high. We report a new high heat induced fibrillizat ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 2
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