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Št. zadetkov: 3
Urinary uremic toxin signatures and the metabolic index of gut dysfunction (MIGD) in autism spectrum disorder
Joško Osredkar, Teja Fabjan, Kristina Kumer, Maja Jekovec-Vrhovšek, Joanna Giebułtowicz, Barbara Bobrowska-Korczak, Gorazd Avguštin, Uroš Godnov
Izvirni znanstveni članek
Oznake: autism spectrum disorder;uremic toxins;microbiota–host interactions;p-cresyl sulfate;indoxyl sulfate;gut metabolic dysfunction;urinary biomarkers;Bristol stool chart;
Gut-derived uremic toxins may play a key role in neurodevelopmental conditions such as autism spectrum disorder (ASD) via host-microbe metabolic interactions. We evaluated five uremic toxins—p-cresyl sulfate (PCS), indoxyl sulfate (IS), trimethylamine N-oxide (TMAO), asymmetric dimethylarginine (ADM ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Systemic uremic toxin burden in autism spectrum disorder
Joško Osredkar, Teja Fabjan, Uroš Godnov, Maja Jekovec-Vrhovšek, Joanna Giebułtowicz, Barbara Bobrowska-Korczak, Gorazd Avguštin, Kristina Kumer
Izvirni znanstveni članek
Oznake: autism spectrum disorder;uremic toxins;p-cresyl sulfate;indoxyl sulfate;metabolomics;urinary biomarkers;gut microbiota;TMAO;ADMA;
Autism spectrum disorder (ASD) is increasingly associated with microbial and metabolic disturbances, including the altered production of gut-derived uremic toxins. We investigated urinary concentrations of five representative uremic toxins—indoxyl sulfate (IS), p-cresyl sulfate (PCS), trimethylamine ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Relationship between excreted uremic toxins and degree of disorder of children with ASD
Joško Osredkar, Barbara Žvar Baškovič, Petra Finderle, Barbara Bobrowska-Korczak, Paulina Gątarek, Angelina Rosiak, Joanna Giebułtowicz, Maja Jekovec-Vrhovšek, Joanna Kałużna-Czaplińska
Izvirni znanstveni članek
Oznake: uremic toxins;autism spectrum disorder;ASD;degree of deficit;
Autism spectrum disorder (ASD) is a complex developmental disorder in which communication and behavior are affected. A number of studies have investigated potential biomarkers, including uremic toxins. The aim of our study was to determine uremic toxins in the urine of children with ASD (143) and co ...
Leto: 2023 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 3
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