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Št. zadetkov: 2
Pharmaceutical solid form screening and selection
Praveen Chappa, Ramesh Naidu Jenjeti, Jakob Kljun, Sudhir Mittapalli, Arthur Pichler, Gautam R. Desiraju
Izvirni znanstveni članek
Oznake: polimorf;aktivne farmacevtske učinkovine;kristalizacija;vodikova vez;polymorph;active pharmaceutical ingredients;crystallization;hydrogen bond;
Solid form screening is an essential step in drug discovery and development because different solid forms of a drug substance may significantly affect the stability, dissolution, and/or manufacturing of the corresponding drug products. This paper takes up these issues, aiming to provide practical gu ...
Leto: 2025 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Co-crystals, salts or mixtures of both? The case of tenofovir alafenamide fumarates
Hannes Lengauer, Damjan Makuc, Damjan Šterk, Franc Perdih, Arthur Pichler, Tina Trdan Lušin, Janez Plavec, Zdenko Časar
Izvirni znanstveni članek
Oznake: co-crystal;salt;polymorphism;X-ray dffraction;
Tenofovir alafenamide fumarate (TAF) is the newest prodrug of tenofovir that constitutes several drug products used for the treatment of HIV/AIDS. Although the solid-state properties of its predecessor tenofovir disoproxil fumarate have been investigated and described in the literature, there are no ...
Leto: 2020 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 2
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