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Imputation of untreated LDL-C in treated subjects with homozygous familial hypercholesterolaemia
John Mancini, Arnold Ryomoto, Isabelle Ruel, Iulia Iatan, Frederick J. Raal, Raul D. Santos, Urh Grošelj
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Oznake: homozygous familial hypercholesterolaemia;low density lipoprotein-cholesterol;imputation;LDL-receptor;lipid lowering therapy;estimated untreated low-density lipoproteincholesterol;
Background and aims: Diagnosis of Homozygous Familial Hypercholesterolaemia (HoFH) relies on untreated low-density lipoprotein-cholesterol (LDL-C) which is often unknown. We determine whether untreated LDL-C can be imputed from treated LDL-C in HoFH. Methods: Two groups with HoFH were identified: Gr ...
Leto: 2026 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
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