Št. zadetkov: 10
Kratki znanstveni prispevek
Oznake:
DNA purification;PFGE plugs;genotyping;bacterial isolates;WGS;
Whole-genome sequencing (WGS) has replaced Pulsed-field gel electrophoresis (PFGE)-based bacterial genotyping as the reference genotyping method. We investigated the suitability of purified genomic DNA extracted from PFGE agarose plugs stored in a laboratory collection for WGS in cases where bacteri ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Magistrsko delo
Oznake:
celična imunoterapija;limfociti T;elektrogenski transfer;himerni antigenski receptor;
Celična imunoterapija je trenutno eno najobetavnejših, hitro razvijajočih terapevtskih področij. Himerni antigenski receptor (CAR) je sintezni molekulski konstrukt, ki je z različnimi metodami genskega transferja vstavljen v limfocite T. To jim omogoča vezavo antigenov, tarčnih receptorjev in uniče ...
Leto:
2019
Vir:
Biotehniška fakulteta (UL BF)
Izvirni znanstveni članek
Oznake:
MRSA;bloodstream infections;whole genom sequencing;Slovenia;
Purpose: Data on the molecular epidemiology of methicillin-resistant Staphylococcus aureus isolates from patients with bacteraemia in Slovenia are lacking. The aim of this study was to phenotypically and genotypically investigate 82 MRSA strains isolated from patients with bloodstream infections in ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Slovenia;Borrelia lusitaniae;tick;Ixodes ricinus;WGS;plasmid analysis;
Background Vector-borne diseases are becoming increasingly important in public health. The incidence of Lyme borreliosis in Slovenia continues to rise. Therefore, screening the prevalence of Borrelia spp. in vectors and their hosts is very important. Rarely, but still, it is possible to discover new ...
Leto:
2025
Vir:
Fakulteta za matematiko, naravoslovje in informacijske tehnologije Koper (UP FAMNIT)
Izvirni znanstveni članek
Oznake:
16S rRNA metabarcoding;bioinformatics;campylobacter;metagenomics;NGS;
Objective: This study aimed to employ advanced bioinformatics and modern sequencing approaches to solve a diagnostic problem of persistent Campylobacter spp. molecular detection yet negative culture results from four consecutive stool samples of a previously healthy patient with newly diagnosed sele ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Campylobacter concisus;WGS;virulence factors;
Campylobacter concisus is recognized as a potential pathogen in gastrointestinal diseases, particularly in patients with chronic intestinal diseases. This study investigates the genomic characteristics, phylogenetic distribution, virulence factors, resistance genes and presence of plasmids in C. con ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Kratki znanstveni prispevek
Oznake:
Mycoplasma arginini;Slovenia;arthritis;bacteria;cellulitis;immunocompromised;kidney transplant recipient;zoonoses;
Mycoplasma arginini is a bacterium primarily found in animals and is seldom reported in human infections. We identified M. arginini infection in a severely immunocompromised kidney transplant recipient in Slovenia. Clinicians should be aware of M. arginini's potential as a pathogen in immunocompromi ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Magistrsko delo
Oznake:
rak želodca;genetski dejavniki;genetski polimorfizmi;polimorfizmi posameznega nukleotida;genetska variabilnost;SMC1B;
Rak želodca je maligni tumor, ki vznikne v želodčni sluznici, lahko pa tudi iz žleznih ali limfatičnih celic v steni želodca. Je peto najpogostejše rakavo obolenje na svetu in tretji najpogostejši vzrok smrti, povezane z rakom. Kljub napredkom v diagnostiki in zdravljenju ostaja petletno preživetje ...
Leto:
2020
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
bisphenol A;human granulosa cells;steroidogenesis;apoptosis;steroid hormones;
Bisphenol A (BPA) is a common synthetic chemical compound classified as an endocrine disruptor. It affects multiple physiological systems in the body, including the female reproductive system, particularly granulosa cells (GCs) in the ovaries, where steroidogenesis occurs. This study investigated th ...
Leto:
2025
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Izvirni znanstveni članek
Oznake:
premature ovarian insufciency;essential;non-essential trace elements;biofuids;reproductive health;
Premature ovarian insufficiency (POI) is poorly understood, with causes identified in only 25% of cases. Emerging evidence suggests links between trace elements (TEs) and POI. This study is the first to compare concentrations of manganese (Mn), copper (Cu), zinc (Zn), selenium (Se), molybdenum (Mo), ...
Leto:
2025
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije