Št. zadetkov: 14
Kratki znanstveni prispevek
Oznake:
DNA purification;PFGE plugs;genotyping;bacterial isolates;WGS;
Whole-genome sequencing (WGS) has replaced Pulsed-field gel electrophoresis (PFGE)-based bacterial genotyping as the reference genotyping method. We investigated the suitability of purified genomic DNA extracted from PFGE agarose plugs stored in a laboratory collection for WGS in cases where bacteri ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Magistrsko delo
Oznake:
celična imunoterapija;limfociti T;elektrogenski transfer;himerni antigenski receptor;
Celična imunoterapija je trenutno eno najobetavnejših, hitro razvijajočih terapevtskih področij. Himerni antigenski receptor (CAR) je sintezni molekulski konstrukt, ki je z različnimi metodami genskega transferja vstavljen v limfocite T. To jim omogoča vezavo antigenov, tarčnih receptorjev in uniče ...
Leto:
2019
Vir:
Biotehniška fakulteta (UL BF)
Izvirni znanstveni članek
Oznake:
MRSA;bloodstream infections;whole genom sequencing;Slovenia;
Purpose: Data on the molecular epidemiology of methicillin-resistant Staphylococcus aureus isolates from patients with bacteraemia in Slovenia are lacking. The aim of this study was to phenotypically and genotypically investigate 82 MRSA strains isolated from patients with bloodstream infections in ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
Slovenia;Borrelia lusitaniae;tick;Ixodes ricinus;WGS;plasmid analysis;
Background Vector-borne diseases are becoming increasingly important in public health. The incidence of Lyme borreliosis in Slovenia continues to rise. Therefore, screening the prevalence of Borrelia spp. in vectors and their hosts is very important. Rarely, but still, it is possible to discover new ...
Leto:
2025
Vir:
Fakulteta za matematiko, naravoslovje in informacijske tehnologije Koper (UP FAMNIT)
Izvirni znanstveni članek
Oznake:
carbapenemase;Escherichia coli;plasmid;population structure;WGS;
Introduction: The incidence of carbapenemase-producing (CP) Escherichia coli has increased worldwide, with the first reports in Europe dating back to the early 2000s. As part of the European Genomic Reference Laboratory Capacity Building (EURGen-RefLabCap) project, Slovenia conducted its first natio ...
Leto:
2026
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
16S rRNA metabarcoding;bioinformatics;campylobacter;metagenomics;NGS;
Objective: This study aimed to employ advanced bioinformatics and modern sequencing approaches to solve a diagnostic problem of persistent Campylobacter spp. molecular detection yet negative culture results from four consecutive stool samples of a previously healthy patient with newly diagnosed sele ...
Leto:
2025
Vir:
Repozitorij Univerze v Ljubljani (RUL)
Izvirni znanstveni članek
Oznake:
Campylobacter concisus;WGS;virulence factors;
Campylobacter concisus is recognized as a potential pathogen in gastrointestinal diseases, particularly in patients with chronic intestinal diseases. This study investigates the genomic characteristics, phylogenetic distribution, virulence factors, resistance genes and presence of plasmids in C. con ...
Leto:
2025
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Kratki znanstveni prispevek
Oznake:
Mycoplasma arginini;Slovenia;arthritis;bacteria;cellulitis;immunocompromised;kidney transplant recipient;zoonoses;
Mycoplasma arginini is a bacterium primarily found in animals and is seldom reported in human infections. We identified M. arginini infection in a severely immunocompromised kidney transplant recipient in Slovenia. Clinicians should be aware of M. arginini's potential as a pathogen in immunocompromi ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
adenomioza;mikrobiom rodil;implantacijsko okno;
Adenomyosis is a chronic gynecological condition affecting a substantial portion of women of reproductive age. With symptoms including abnormal uterine bleeding, chronic pelvic pain (CPP), dysmenorrhea, and infertility, poor response to symptomatic treatment and unfavorable outcomes of assisted repr ...
Leto:
2026
Vir:
Medicinska fakulteta (UL MF)
Eva Ružić-Sabljić,
Daša Podgoršek,
Katja Strašek,
Andraž Celar Šturm,
Mateja Logar,
Andrea Pavlović,
Tatjana Remec-Zafred,
Zvonko Baklan,
Emil Pal,
Tjaša Cerar,
Tjaša Cerar
Izvirni znanstveni članek
Oznake:
Leptospira sp.;leptospirosis;Slovenia;1fb gene;MALDI-TOF;NotI-RFLP;MLST;WGS;
Leptospirosis is an important worldwide zoonosis, and it has also been reported in Slovenia. The cultivation of Leptospira from human material is difficult. Despite that, we successfully isolated 12 human Leptospira strains isolated from patients between 2002 and 2020 and used various methods for th ...
Leto:
2023
Vir:
Repozitorij Univerze v Ljubljani (RUL)