Št. zadetkov: 12
Doktorska disertacija
Oznake:
vaskulitis;klinična manifestacija;klasifikacija;incidenca;Slovenija;Slovenia;
Vaskulitis IgA pri odraslih
Leto:
2018
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
gigantocelični arteritis;ultrazvok;halo znak;preoblikovanje arterijske stene;biopsija temporalne arterije;mikro RNA;vnetje;imunopatologija;diagnoza;vaskulitis;
Uvod: Poglavitni namen doktorskega dela je bil pridobiti dodaten vpogled v patogenetske mehanizme gigantoceličnega arteritisa (GCA) in povezati le-te z ultrazvočno preiskavo arterij (danes preiskavo izbora v diagnostiki gigantoceličnega vaskulitisa). V raziskavah, opravljenih v okviru doktorskega de ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
IgA vaskulitis pri odraslih;NK-celice;biomarkerji;sistemska skleroza;kordicepin;
IgA vaskulitis (IgAV) in sistemska skleroza (SSc) sta sistemski avtoimunski bolezni, ki znatno prizadeneta kožo, vendar se njuna patofiziologija močno razlikuje. Pri IgAV je akutno vnetje kože posledica aktivacije prirojenega imunskega sistema, vendar so nekatere njegove komponente, kot so NK celice ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
giant cell arteritis;epigenetics;microRNA;inflammation;vascular remodeling;biomarker;
Giant cell arteritis (GCA) is a primary systemic vasculitis affecting the elderly, characterized by a granulomatous vessel wall inflammation of large- and medium-sized arteries. The immunopathology of GCA is complex, involving both the innate and adaptive arms of the immune system, where a maladapti ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
giant cell arteritis;temporal artery biopsy;inflammation;
Objectives: The aim of this study was to quantitatively assess distinct immune cell subsets comprising inflammatory infiltrate in temporal artery biopsies (TABs) from patients with giant cell arteritis (GCA), and to link the obtained histopathological data with expression profiles of immune-related ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
giant cell arteritis;ultrasonography;arterial remodeling;
The aim of this study was to assess the interrelation between vascular ultrasonography (US) findings, histopathological data, and the expression of selected dysregulated microRNAs (miRNAs) in giant cell arteritis (GCA). The study included data on the clinical parameters, US measurements, and tempora ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
epidemiology;rheumatology;tuberculosis;
Objectives: This study aimed to assess the risk of tuberculosis (TB) in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) treated with any of the commercially available tumour necrosis factor inhibitors (TNFis) in Slovenia. Design: This is a cohort, r ...
Leto:
2020
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Izvirni znanstveni članek
Oznake:
antineutrophil cytoplasmic antibodies (ANCA);proteinase 3 (PR3);myeloperoxidase (MPO);ANCA-associated vasculitis (AAV);chemiluminescent immunoassay;likelihood ratios (LRs);
Objectives: Antineutrophil cytoplasmic antibody (ANCA) testing assists clinicians diagnose ANCA-associated vasculitis (AAV). We aimed to verify and harmonize chemiluminescent immunoassays for the detection of myeloperoxidase (MPO)- and proteinase 3 (PR3)-ANCA. Methods: An in-house ELISA, a capture E ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
velikanski celični arteritis;mikroRNA;preoblikovanje arterij;giant cell arteritis;microRNA;arterial remodelling;
In this study, we explored expression of microRNA (miR), miR-target genes and matrix remodelling molecules in temporal artery biopsies (TABs) from treatment-naïve patients with giant cell arteritis (GCA, n = 41) and integrated these analyses with clinical, laboratory, ultrasound and histological man ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
cryoglobulins;cryoglobulinemic vasculitis;rheumatoid factor activity;complement components;cryoglobulin detection;pre-analytical phase;
The detection of cryoglobulins (CG) used to diagnose cryoglobulemic vasculitis requires strict adherence to protocol, with emphasis on the preanalytical part. Our main objectives were to introduce a more sensitive and specific protocol for the detection of CG and to characterize CG in Slovenian pati ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)