Št. zadetkov: 26
Izvirni znanstveni članek
Oznake:
suicidal behaviour;epigenetics;next-generation sequencing;
Objectives Epigenetic mechanisms are involved in regulation of many pathologies, including suicidal behaviour. However, the factors through which epigenetics affect suicidal behaviour are not fully understood. Methods We analysed DNA methylation of eight neuropsychiatric genes (NR3C1, SLC6A4, HTR1A, ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
ADORA2A;B4GALT2;ChIP-seq;chromatin immunoprecipitation;epigenetics;H3K14ac;MMP14;sequencing;suicide;
Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to changes of chromatin (de)condensation and consequently gene expression. Materials & methods: Level of H3K14ac was studied with chromatin immunoprecipitation fol ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
CSF;EVs;Slovene male suicides;epigenetics;miR-19a-3p;miR-4516;miRNA expression;micro RNA;suicidal behavior;suicide;
Suicide is an important public-health concern, with more than 700,000 people dying by suicide yearly. It is a multifactorial phenomenon, shaped by the effects of sociodemographic, environmental and biological factors. The latter two factors can be linked through epigenetic studies, which examine dif ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
population of the Balkans;Y-SNP haplogroups;forensic application;
The genetic structure of the Balkan peoples is complex and is reflection of continuous migration processes and settlement of various tribes and ethnic groups throughout past centuries. The human uniparental genetic markers, the Y-chromosome and mitochondrial DNA are widely used for studying populati ...
Leto:
2024
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
nanomateriali;rak možganov;nanomedicina;nanomaterials;brain cancer;nanomedicine;
Advances in technology of the past decades led to development of new nanometer scale diagnosis and treatment approaches in cancer medicine leading to establishment of nanooncology. Inorganic and organic nanomaterials have been shown to improve bioimaging techniques and targeted drug delivery systems ...
Leto:
2019
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
Suicide is a complex phenomenora that is triggered by environmental factors, and probably partially also by genetic code. Genetic studies performed on suicide brain contributed interesting, findings on serotonergic, dopaminergic and noradrenergic neurotransmitter systems and on cholesterol system as ...
Leto:
2006
Vir:
dLib.si Digitalna knjižnica Slovenije
Video in druga učna gradiva
Oznake:
medicine;psychiatry
Leto:
2012
Vir:
videolectures.net
Doktorska disertacija
Oznake:
duševne motnje;samomori;patogeneza;nevrotrofini;receptorji;možganski nevrotrofni dejavnik;genotipizacija;epigenetika;metilacija DNA;gensko izražanje;možgani;kri;Slovenia;Slovenija;
Povezava genetskih in epigenetskih sprememb v genih nevrotrofnega sistema s samomorom
Leto:
2017
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
dolgo nekodirana RNA;shizofrenija;depresija;long noncoding RNA;schizophrenia;depression;
Understanding the pathology of psychiatric disorders is challenging due to their complexity and multifactorial origin. However, development of high-throughput technologies has allowed for better insight into their molec-ular signatures. Advancement of sequencing methodologies have made it possible t ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Hana Dema,
Alja Videtič,
Alja Videtič,
Katarina Kouter,
Mojca Katrašnik,
Mojca Jensterle Sever,
Andrej Janež,
Aleš Oblak,
Borut Škodlar,
Jurij Bon,
Jurij Bon
Izvirni znanstveni članek
Oznake:
program zmanjševanja stresa, ki temelji na čuječnosti;polycystic ovary syndrome;DNA methylation;mindfulness-based stress reduction program;
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder affecting women of reproductive age. Research has shown that epigenetic alterations such as DNA methylation may play a role in the development and progression of abnormal ovarian function and metabolic disorders in PCOS. Studies ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)