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Št. zadetkov: 4
Integration of omics data to generate and analyse COVID-19 specific genome-scale metabolic models
Tadeja Režen, Alexandre Martins, Miha Mraz, Nikolaj Zimic, Damjana Rozman, Miha Moškon
Izvirni znanstveni članek
Oznake: COVID-19;metabolni modeli na nivoju genoma;metode ekstrakcije modelov;kontekstno specifični modeli;metabolna analiza obogatenosti;genome-scale metabolic models;model extraction methods;context-specific models;metabolic enrichment analysis;
COVID-19 presents a complex disease that needs to be addressed using systems medicine approaches that include genome-scale metabolic models (GEMs). Previous studies have used a single model extraction method (MEM) and/or a single transcriptomic dataset to reconstruct context-specific models, which p ...
Leto: 2022 Vir: Fakulteta za računalništvo in informatiko (UL FRI)
Search for neutrons from Galactic sources with the Pierre Auger Observatory
Miguel Alexandre Martins, Andrej Filipčič, J. P. Lundquist, S. U. Shivashankara, Samo Stanič, Serguei Vorobiov, Danilo Zavrtanik, Marko Zavrtanik
Objavljeni znanstveni prispevek na konferenci
Oznake: ultra-high-energy cosmic rays;Pierre Auger Observatory;UHE neutrons;Galactic sources;Crab Nebula;
Astrophysical neutral particles, such as neutrons, are produced through interactions of charged cosmic rays in the vicinity of their acceleration sites and are not deflected by magnetic fields during propagation. Therefore, they can be traced back to their sources. Despite being unstable particles, ...
Leto: 2025 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Structure–activity relationship and crystallographic study of new monobactams
Vid Kavaš, Carlos Contreras-Martel, Stane Pajk, Damijan Knez, Alexandre Martins, Thomas A. Gould, David I. Roper, Irena Zdovc, Andréa Dessen, Martina Hrast, Stanislav Gobec
Izvirni znanstveni članek
Oznake: antimicrobial agents;bacteria inhibition;inhibitors;potassium;
Monobactams, a subclass of β-lactam antibiotics with a monocyclic scaffold, are uniquely resistant to hydrolysis by metallo-β-lactamases, providing a distinct therapeutic advantage. Here, we report an in silico-based structure–activity relationship (SAR) investigation of aztreonam-related monobactam ...
Leto: 2026 Vir: Fakulteta za farmacijo (UL FFA)
ǂThe ǂbenefits, costs and feasibility of a low incidence COVID-19 strategy
Thomas Czypionka, Emil Nafis Iftekhar, Barbara Prainsack, Viola Priesemann, Simon Bauer, André Calero Valdez, Sarah Cuschieri, Enrico Glaab, Eva Grill, Jenny Krutzinna, Christos Lionis, Helena Machado, Carlos Martins, George N Pavlakis, Matjaž Perc, Elena Petelos, Martyn Pickersgill, Alexander Skupin, Eva S. Schernhammer, Ewa Szczurek, Sotirios Tsiodras, Peter Willeit, Paul Wilmes
Izvirni znanstveni članek
Oznake: dinamika bolezni;eksponentna rast;viralnost;strategija;ne zaključna dela;disease dynamics;exponential growth;virality;strategy;
In the summer of 2021, European governments removed most NPIs after experiencing prolonged second and third waves of the COVID-19 pandemic. Most countries failed to achieve immunization rates high enough to avoid resurgence of the virus. Public health strategies for autumn and winter 2021 have range ...
Leto: 2022 Vir: Fakulteta za naravoslovje in matematiko (UM FNM)
Št. zadetkov: 4
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