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Gene expression profiles associated with carboplatin chemoresistance in high-grade serous ovarian cancer
Vesna Kokondoska Grgič, Nika Marolt, Ajla Kubat, Tamara Dokmanović, Katja Kološa, Ivana Jovchevska, Tea Lanišnik-Rižner, Tea Lanišnik-Rižner
Izvirni znanstveni članek
Oznake: 3D ovarian cancer models;carboplatin;chemoresistance;biomarkers;transcriptomics;
Carboplatin resistance remains a major challenge in the treatment of high-grade serous ovarian cancer (HGSOC), the most lethal subtype of epithelial ovarian cancer. To uncover mechanisms driving chemoresistance, we combined patient-derived transcriptomic data with advanced 3D in vitro models. Analys ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
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