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Št. zadetkov: 5
Adhesion and stiffness of detached breast cancer cells in vitro
Špela Zemljič Jokhadar, Špela Zemljič Jokhadar, Gašper Kokot, Mojca Pavlin, Jure Derganc
Izvirni znanstveni članek
Oznake: metastatic potential;adhesion to epithelial cells;optical tweezers;
Metastatic cancer cells can overcome detachment-induced cell death and can proliferate in anchorage-independent conditions. A recent study revealed that a co-treatment with two drugs that interfere with cell metabolism, metformin and 2-deoxy-D-glucose, promotes detachment of viable MDA-MB-231 breast ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂpore-forming action of polyenes
Luka Kristanc, Bojan Božič, Špela Zemljič Jokhadar, Marija Sollner Dolenc, Gregor Gomišček
Pregledni znanstveni članek
Oznake: polyenes;sterols;pore forming;tension pore;osmotic stress;
The incidence of resistant fungal pathogens has been increasing, especially in immuno-compromised people. As such, considerable research has been focused on discovering anti-fungal agents with new mechanisms of action and on optimizing the use of existing agents. In this context, interest in the pol ...
Leto: 2019 Vir: Fakulteta za farmacijo (UL FFA)
Shear flow deformability cytometry
Lija Fajdiga, Špela Zemljič Jokhadar, Tadej Kokalj, Tadej Kokalj, Jure Derganc, Jure Derganc
Pregledni znanstveni članek
Oznake: deformability cytometry;microfluidics;cell mechanics;mechanical biomarkers;blood analysis;disease;single-cell;clinical method;
Background Shear flow deformability cytometry is an emerging microfluidic technique that has undergone significant advances in the last few years and offers considerable potential for clinical diagnostics and disease monitoring. By simultaneously measuring mechanical and morphological parameters of ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Induced pluripotent stem cell (iPSC) line MLi-004A derived from a patient with recessive dystrophic epidermolysis bullosa (RDEB)
Sandra Ropret, Jakob Jeriha, Tjaša Sorčan, Marija Rogar, Špela Zemljič Jokhadar, John A. McGrath, Dusko Ilic, Mirjana Liović
Izvirni znanstveni članek
Oznake: matične celice;epidermoliza;kolagen VII;stem cell;epidermolysis;collagen VII;
We have generated MLi004-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a female patient with recessive dystrophic epidermolysis bullosa (RDEB). This iPSC line may be used as a model system for studies on skin integrity, the extracellular matrix and skin barrier ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Keratin dynamics and spatial distribution in wild-type and K14 R125P mutant cells - a computational model
Marcos Gouveia, Hiroko Ikeshima-Kataoka, Špela Zemljič Jokhadar, Marko Vidak, Biljana Stojković, Jure Derganc, Rui Travasso, Mirjana Liović
Izvirni znanstveni članek
Oznake: keratin;epidermoliza bullosa simplex;mutacija;epidermolysis bullosa simplex;mutation;
Keratins are one of the most abundant proteins in epithelial cells. They form a cytoskeletal filament network whose structural organization seriously conditions its function. Dynamic keratin particles and aggregates are often observed at the periphery of mutant keratinocytes related to the hereditar ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 5
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