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Altered NRF2 signalling in systemic redox imbalance: Insights from non-communicable diseases
Monika Jakubowska, Vera Marisa Costa, Wojciech Krzeptowski, Pia Pužar Dominkuš, Marlene Santos, Birsen Can Demirdöğen, Şermin Genç, Ioannis P. Trougakos, Katja M. Kanninen, Brigitte M. Winklhofer-Roob, Vita Dolžan
Pregledni znanstveni članek
Oznake: biomarker;NRF2;non-communicable diseases;oxidative stress;radox imbalance;transcription factor;
The balanced activity of the cytoprotective transcription factor NRF2 is central for maintaining redox, metabolic-energetics, and proteome homeostasis, as well as for regulating inflammatory responses, among other functions. Activated NRF2 regulates the expression of hundreds of genes containing ant ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
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